All Publications

Each year, GRIP awards 8-10 recipients a grant for research. Several grant investigators have published over the years. Please find them highlighted below. Additionally, most abstracts can be located on Pub Med.

2009 - Cycle 8
White, Kenneth
PUBLICATION(s):
Farrow EG and White KE. Recent advances in renal phosphate handling. Invited review. Nature Reviews Nephrology. 2010 Apr;6(4):207-17
Farrow E, Summers L, Schiavi S, et al. Altered Renal FGF23-Mediated Activity Involving MAPK and Wnt: Effects of the Hyp Mutation. J Endocrinol. 2010; Jul 30.
2008 - Cycle 7
Badano, Jose
PUBLICATION(s):
Cardenas-Rodriguez M and Badano J. Ciliary Biology: Understanding the Cellular and Genetic Basis of Human Ciliopathies. American Journal of Medical Genetics Part C (Seminars in Medical Genetics). 2009; 151C:263–280
Feng, Jerry
PUBLICATION(s):
Lu Y, Yuan B, Qin C, et al. The biological function of DMP1 in osteocyte maturation is mediated by its 57 kDa C-terminal fragment. Journal of Bone and Mineral Research. 2010 Aug 23.
Lu Y, Feng JQ. FGF23 in skeletal modeling and remodeling. Curr Osteoporos Rep. 2011 Jun;9(2):103-8.
Zhang R, Lu Y, Ye L, et al. Unique Roles of Phosphorus in Endochondral Bone Formation and Osteocyte Maturation. Bone Miner Res. 2011 May;26(5):1047-56. doi: 10.1002/jbmr.294.
Lu Y, Yuan B, Qin C, et al. The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. J Bone Miner Res. 2011 Feb;26(2):331-40. doi: 10.1002/jbmr.226.
2007 - Cycle 6
Dwyer, Karen

PUBLICATION(s):
Lu B, Rajakumar V, Robson S, et al. The Impact of Purinergic Singnaling on Renal Ischemia-Reperfusion Injury. Transplantation. 2008;86: 1707-1712.
Humphreys, Benjamin

PUBLICATION(s):
Humphreys B, Valerius M, Kobayashi A, et al. Intrinsic Epithelial Cells Repair the Kidney after Injury. Cell Stem Cell. 2008; 2, 284-291.
Kitching, Richard

PUBLICATION(s):
Kuligowski M, Kwan R, Lo C, et al. Antimyeloperoxidase antibodies rapidly induce {alpha}4-integrin-dependent glomerular neutrophil adhesion. Blood. 2009;113: 6485-6494.
van Zonneveld, Anton-Jan

PUBLICATION(s):
van Solingen C, Seghers L, Bijkerk R, et al. Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesis. J. Cell. Mol. Med. 2009;Vol 13, No 2, pp. 1-9.
2006 - Cycle 5
Duffield, Jeremy

PUBLICATION(s):
Lin S, Kisseleva T, Brenner D, et al. Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney. The American Journal of Pathology., 2008;Vol. 173, No. 6.
Lin S, Castano A, Nowlin B, et al. Bone Marrow Ly6Chigh Monocytes Are Selectively Recruited to Injured Kidney and Differentiate into Functionally Distinct Populations. The Journal of Immunology. 2009; Nov 15;183(10):6733-43.
Castaño A, Lin S, Surowy T, et al. Serum Amyloid P Inhibits Fibrosis Through FcgR-Dependent Monocyte-Macrophage Regulation in Vivo. Science Translational Medicine., 2009; 4 November Vol 1 Issue 5 5ra13.
Lin S, Li B, Rao S, et al. Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci USA.em> 2010 Mar 2;107(9):4194-9.
Hughey, Rebecca

PUBLICATION(s):
Mattila P, Kinlough C, Bruns J, et al. MUC1 traverses apical recycling endosomes along the biosynthetic pathway in polarized MDCK cells. Biol. Chem. 2009; Jul 390(7):551-6.
Poland P, Rondanino C, Kinlough CL, et all. Identification and characterization of endogenous galectins expressed in Madin Darby canine kidney cells. J. Biol. Chem.. 2011 Feb 25;286(8):6780-90. Epub 2010 Dec 2.
Kelley, Vicki

PUBLICATION(s):
Menke J, Lucas J, Zeller G, et al. Programmed Death 1 Ligand (PD-L) 1 and PD-L2 Limit Autoimmune Kidney Disease: Distinct Roles The Journal of Immunology. 2007;0022-1767/07
Lucas J, Menke J, Rabacal W, et al. Programmed Death Ligand 1 Regulates a Critical Checkpoint for Autoimmune Myocarditis and Pneumonitis in MRL Mice. The Journal of Immunology. 2008;0022-1767/08
Levine, Jerrold

PUBLICATION(s):
Iglesias J, DePalma L, Hom D, et al. Predictors of mortality in adult patients with congestive heart failure receiving nesiritide—Retrospective analysis showing a potential adverse interaction between neseritide and acute renal dysfunction. Nephrol Dial Transplant., 2008;23:144-153.
Patel V, Lee D, Longacre-Antoni A, et. al. Apoptotic and necrotic cells as sentinels of local tissue stress and inflammation: Response pathways initiated in nearby viable cells. Autoimmunity. 2009; 42(4): 317–321
Antoni A, Graham L, Rauch J, et al. Altered cell–cell and cell–matrix interactions in the development of systemic autoimmunity. Autoimmunity. 2009; 42(4): 278–281
Lieberthal W and Levine J. The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease. J Am Soc Nephrol. 2009; 20: 2493–2502
Dieude M, Gillis M, Theoret J, et al. Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis. Journal of Thrombosis and Haemostasis. 2009;7: 710–719.
Tolomeo T, Rico De Souza A, Roter E, et al. T cells demonstrate a Th1-biased response to native b2-glycoprotein I in a murine model of anti-phospholipid antibody induction. Autoimmunity 2009; 42(4): 292–295
Patel V, Lee D, Feng L, et al. Recognition of Apoptotic Cells by Epithelial Cells. The Journal of Biological Chemistry. 2010;Vol. 285, NO. 3, pp. 1829-1840.
2005 - Cycle 4
Antignac, C. & Esquivel, E.

PUBLICATION(s):
Ratelade J, Lavin TA, Muda AO, et al. Maternal environment interacts with modifier genes to influence progression of nephrotic syndrome. J Am Soc Nephrol. 2008 Aug;19(8):1491-9.
Féraille, Eric

PUBLICATION(s):
Leroy V, De Seigneux S, Agassiz V, et al. Aldosterone Activates NF-kB in the Collecting Duct. J Am Soc Nephrol. 2009;20:131-144.
Ronco, Pierre

PUBLICATION(s):
Ronco P, Debiec H. Molecular dissection of target antigens and nephritogenic antibodies in membranous nephropathy; towards epitope-driven therapies. J Am Soc Nephrol 2006, 17(7):1772-74.
Ronco P, Debiec H. New insights into membranous glomerulonephritis. Curr Opin Nephrol Hypertens 2006, 15(3): 258-63.
Debiec H, Ronco M. Fetomaternal alloimmunization with antenatal glomerulopathies. Ann NY Acad Sci, 2007, 1110:559-66.
Ronco P, Debiec H. Podocyte Antigens and Glomerular Disease Nephron Exp Nephrol. 2007, 107:41-46.
Ronco P, Debiec H. Target antigens and nephritogenic antibodies in membranous nephropathy : of rats and men Seminars in Immunopathol. 2007, 29:45-58.
Ronco P, Debiec H. Target antigens and nephritogenic antibodies in membranous nephropathy. Arch Med Sci, 2009, 5 : S442-S450.
2004 - Cycle 3
Bradley, John

PUBLICATION(s):
Al-Lamki R, Wang J, Tolkovsky A, et al. TL1A Both Promotes and Protects from Renal Inflammation and Injury. J Am Soc Nephrol. 2008;19: 953-960.
Noris, Marina

PUBLICATION(s):
Tomasoni S, Aiello S, Cassis L, et al. Dendritic cells genetically engineered with adenoviral vector encoding dnIKK2 induce the formation of potent CD4+ T-regulatory cells. Transplantation 2005;79:1056-1061.
Aiello S, Cassis P, Cassis L, et al. DnIKK2-transfected dendritic cells induce a novel population of inducile nitric oxide synthase-expressing CD+ CD25- cells with tolerogenic properties. Transplantation 2007;83:474-484.
Williams, Julie

PUBLICATION(s):
Williams J and Savage, C. Characterization of the regulation and functional consequences of p21ras activation in neutrophils by antineutrophil cytoplasm antibodies. J Am Soc Nephrol. 2005; Jan 16(1):90-6.
Williams J, Pettitt T, Powell W, et al. Antineutrophil Cytoplasm Antibody-Stimulated Neutrophil Adhesion Depends on Diacylglycerol Kinase-Catalyzed Phosphatidic Acid Formation. J Am Soc Nephrol. 2007;18: 1112-1120.
Wong, Wilson

PUBLICATION(s):
Brown K, Moxham V, Karegli J, et al. Ultra-Localization of Foxp3 T Cells within Renal Allografts Shows Infiltration of Tubules Mimicking Rejection. The American Journal of Pathology. 2007:171; 1915-1922.
Brown K and Wong W. Diagnostic Value of Regulatory T Cells: A New Facet of a Much Studied Cell Population. Transplantation. 2008;86:Transplantation. 2008 Dec 15;86(11):1485-91
Brown K, Sacks S, and Wong W. Extensive and bidirectional transfer of major histocompatibility complex class II molecules between donor and recipient cells in vivo following solid organ transplantation. The FASEB Journal. 2008; Vol. 22.
Brown K and Wong W. Monitoring Regulatory T-Cells after Transplantation: Is It Useful. Trends in Transplant. 2009;3:119-28.
2003 - Cycle 2
Jonsson, Kenneth

PUBLICATION(s):
Marsell R, Krajisnik T, Goransson H, et al. Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23.Nephrol Dial Transplant. 2008 Mar;23(3):827-33.
Morigi, Marina

PUBLICATION(s):
Buelli S, Abbate M, Morigi M, et al. Protein load impairs factor H binding promoting complement-dependent dysfunction of proximal tubular cells. Kidney International. 75:1050-1059. 2009.
O'Neill, W. Charles

PUBLICATION(s):
Lomashvili K, Cobbs S, Hennigar R, et al. Phosphate-Induced Vascular Calcification: Role of Pyrophosphate and Osteopontin. J Am Soc Nephrol. 2004;15: 1392–1401.
Lomashvili K, Khawandi W, and O’Neill WC. Reduced Plasma Pyrophosphate Levels in Hemodialysis Patients. the American Society of Nephrology. 2005;1046-6673/1608-2495.
Lomashvili K, Garg P and WC O’Neill. Chemical and hormonal determinants of vascular calcification in vitro. Kidney International. 2006;69, 1464–1470.
O'Neill WC. The fallacy of calcium-phosphorus product. Kidney International. 2007;72, 792–796;
Lomashvili K, Garg P, Narisawa S, et al. Upregulation of alkaline phosphatase and pyrophosphate hydrolysis: Potential mechanism for uremic vascular calcification. Kidney International. 2008; doi:10.1038/ki.2008.26.
O'Neill WC. Treatment of vascular calcification. Kidney International. 2008;74, 1376–1378.
Lomashvili K, Monier-Faugere M, Wang X, et al. Effect of bisphosphonates on vascular calcification and bone metabolism in experimental renal failure. Kidney International. 2009;75, 617-625.
Sandberg, Kathryn

PUBLICATION(s):
Ji H, Zheng W, Menini S, et al. Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production. Gend Med. 2007;Mar;4(1):56-71.
Ji H, Pesce C, Zheng W, et al. Sex differences in renal injury and nitric oxide production in renal wrap hypertension. Am J Physiol Heart Circ Physiol. 2005;288: H43–H47, 2005.
2002 - Cycle 1
Alpers, Charles

PUBLICATION(s):
Muhlfeld A, Segerer S, Hudkins K, et al. Deletion of the Fc Receptor IIb in Thymic Stromal Lymphopoietin Transgenic Mice Aggravates Membranoproliferative Glomerulonephritis. American Journal of Pathology. 2003;Vol. 163 No. 3.
Taneda S, Hudkins K, Muhlfeld A, et al. Protease Nexin-1, tPA, and PAI-1 are Upregulated in Cryoglobulinemic Membranoproliferative Glomerulonephritis. J Am Soc Nephrol. 2008;19: 243–251.
Benigni, Ariela

PUBLICATION(s):
Benigni A, Tomasoni S, Turka, L, et al. Adeno-associated virus-mediated CTLA4Ig gene transfer protects MHC-mismatched renal allografts from chronic rejection. J Am Soc Nephrol. 2006;17:1665-1672.
Mayer, Gert

PUBLICATION(s):
Koppelstaetter C, Schratzberger G, Preco P, et al. Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation. Aging Cell 2008;Aug 7(4):491-7.
Pontoglio, Marco

PUBLICATION(s):
Gresh L, Fischer E, Reimann A, et al. A transcriptional network in polycystic kidney disease. The EMBO Journal. 2004;23, 1657–1668.
Fischer E, Legue E, Doyen A, et al. Defective planar cell polarity in polycystic kidney disease. Nature Genetics. 2006;Vol 38, No. 1.
Contact

For questions regarding the GRIP application process, please email our Grant Program Administrator.

Genzyme Terms and Conditions | Privacy Policy Genzyme Corporation. All rights reserved.